It is the year 2237. After the earth has become uninhabitable due to an ecological collapse, the remaining people live on overcrowded space stations in earth’s orbit. The young doctor Laura Portmann is one of them. She hopes for a better future on the distant planet Rhea. But to get there she needs money. She signs up for a job on the derelict cargo ship Kassandra, heading for a 4 year flight to Station 42.
The crew members spend the most time of the fully automated flight in deep sleep while, in 8 months shifts, always one person stays awake to monitor the space ship. Due to the current terrorist threat there is also an additional security person aboard: Samuel Decker. Toward the end of her shift, Laura Portmann hears unusual noises from the cargo bay, and she feels observed. Her colleagues will be awakened, and together, the crew sets out to investigate the cold cargo space. They make gruesome discoveries.
After the first death, it is clear that on the Kassandra bad things are happening. Everyone begins to distrust the other. Laura Portmann, together with Decker uncovers the real destination of the cargo ship, learns what secret cargo they transport, and discover a large-scale fraud.

Indonesia :
Di tahun 2237, saat bumi sudah hancur, semua orang berlomba-lomba pergi ke planet Rhea untuk mencari kehidupan yang lebih baik. Termasuk Dr. Laura Portmann. Demi mengumpulkan uang ia bekerja di sebuah pesawat kargo Kassandra. Pesawat ini dikendalikan secara otomatis, dan di akhir waktu kerjanya, Laura mendengarkan suara aneh dari kabin kargo. Lalu ia pun mulai mencari tahu sebabnya, namun yang ditemukannya jauh lebih menakutkan, semua penipuan besar-besaran dan fakta mengerikan yang terjadi pada Kassandra sebelumnya.